2WPO
HCMV protease inhibitor complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | HUMAN CYTOMEGALOVIRUS PROTEASE | polymer | 256 | 28178.7 | 4 | UniProt (P16753) Pfam (PF00716) In PDB | Human herpesvirus 5 (Human cytomegalovirus) | |
2 | A, B, C, D | (2S)-2-(3,3-dimethylbutanoylamino)-N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[(4-iodophenyl)methylamino]-4-oxo-butan-2-yl]amino]- 1,4-dioxo-4-pyrrol-1-yl-butan-2-yl]-3,3-dimethyl-butanamide | non-polymer | 709.6 | 4 | BIRD (PRD_000229) Chemie (01E) |
Sequence modifications
A, B, C, D: 1 - 256 (UniProt: P16753)
PDB | External Database | Details |
---|---|---|
Gln 143 | Ala 143 | engineered mutation |
Met 181 | Thr 181 | engineered mutation |
Met 229 | Leu 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 112714.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2838.5 | |
All* | Total formula weight | 115553.2 |