2WOU
ALK5 IN COMPLEX WITH 4-((4-((2,6-dimethyl-3-pyridyl)oxy)-2-pyridyl) amino)benzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TGF-BETA RECEPTOR TYPE-1 | polymer | 306 | 34939.2 | 1 | UniProt (P36897) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I, TGF-BETA RECEPTOR TYPE I, TGF-BETA TYPE I RECEPTOR, TBETAR-I, TGFR-1, SERINE/THREONINE-PROTEIN KINASE RECEPTOR R4, SKR4, ACTIVIN RECEPTOR-LIKE KINASE 5, ALK-5 |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | 4-({4-[(2,6-DIMETHYLPYRIDIN-3-YL)OXY]PYRIDIN-2-YL}AMINO)BENZENESULFONAMIDE | non-polymer | 370.4 | 1 | Chemie (ZZF) | |||
| 4 | D (A) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34939.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 432.5 | |
| All* | Total formula weight | 35371.7 |
