2WOM
Crystal Structure of UK-453061 bound to HIV-1 Reverse Transcriptase (K103N).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV-1 REVERSE TRANSCRIPTASE | polymer | 560 | 64547.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | HUMAN IMMUNODEFICIENCY VIRUS 1 | HIV-1 RT |
| 2 | B | HIV-1 REVERSE TRANSCRIPTASE | polymer | 440 | 51384.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | HUMAN IMMUNODEFICIENCY VIRUS 1 | HIV-1 RT |
| 3 | A | 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile | non-polymer | 310.4 | 1 | Chemie (ZZE) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 690 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Lys 690 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115931.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 310.4 | |
| All* | Total formula weight | 116242.2 |
