2WMX
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SERINE/THREONINE-PROTEIN KINASE CHK1 | polymer | 289 | 33043.0 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 1 |
2 | A | 1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine | non-polymer | 309.4 | 1 | Chemie (ZY6) | |||
3 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33043.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 309.4 | |
All* | Total formula weight | 33352.4 |