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2WMX

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASERINE/THREONINE-PROTEIN KINASE CHK1polymer28933043.01UniProt (O14757)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)CHECKPOINT KINASE 1
2A1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanaminenon-polymer309.41Chemie (ZY6)
3waterwater18.060Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33043.0
Non-Polymers*Number of molecules1
Total formula weight309.4
All*Total formula weight33352.4
*Water molecules are not included.

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PDB entries from 2024-08-28

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