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2WMW

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SERINE/THREONINE-PROTEIN KINASE CHK1polymer28933043.01UniProt (O14757)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)CHECKPOINT KINASE 1
2B
(A)
1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINEnon-polymer312.21Chemie (ZYW)
3C
(A)
waterwater18.084Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33043.0
Non-Polymers*Number of molecules1
Total formula weight312.2
All*Total formula weight33355.2
*Water molecules are not included.

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