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2WMS

Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SERINE/THREONINE-PROTEIN KINASE CHK1polymer28933043.01UniProt (O14757)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)CHECKPOINT KINASE 1
2B
(A)
[4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanonenon-polymer275.41Chemie (ZYS)
3C
(A)
waterwater18.048Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33043.0
Non-Polymers*Number of molecules1
Total formula weight275.4
All*Total formula weight33318.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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