2WIL
AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CHOLINESTERASE | polymer | 529 | 59685.5 | 2 | UniProt (P06276) Pfam (PF00135) | Homo sapiens (Human) | ACYLCHOLINE ACYLHYDROLASE, BUTYRYLCHOLINE ESTERASE, CHOLINE ESTERASE II, PSEUDOCHOLINESTERASE |
| 2 | C, D, E, F (C, D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 4 | In PDB GlyTouCan (G21290RB) | |||
| 3 | G, N (A, B) | ethylphosphoramidic acid | non-polymer | 125.1 | 2 | Chemie (TCX) | |||
| 4 | H, I, J, O, P... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | K, L, R (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | M (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 529 (UniProt: P06276)
| PDB | External Database | Details |
|---|---|---|
| Gln 17 | Asn 45 | engineered mutation |
| Gln 481 | Asn 509 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119370.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2282.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1901.0 | |
| All* | Total formula weight | 123554.1 |
