2WI3
Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HEAT SHOCK PROTEIN, HSP 90-ALPHA | polymer | 236 | 26601.8 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | 4-METHYL-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE | non-polymer | 156.2 | 1 | Chemie (ZZ3) | |||
4 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26601.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 180.5 | |
All* | Total formula weight | 26782.3 |