2WHW

Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CYTOCHROME P450 MONOOXYGENASE	polymer	436	48181.6	2	UniProt (O87605) Pfam (PF00067) In PDB	STREPTOMYCES VENEZUELAE	PIKC
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	CYCLOTRIDECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE	non-polymer		355.6	2	Chemie (1D4)
4	B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	711	Chemie (HOH)

Sequence modifications

A, B: -19 - 0 (PDB: 2WHW)
A, B: 1 - 416 (UniProt: O87605)

PDB	External Database	Details
Asn 50	Asp 50	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96363.3
Non-Polymers*	Number of molecules	6
	Total formula weight	2136.2
All*	Total formula weight	98499.5

*Water molecules are not included.