2WGS

Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	GLUTAMINE SYNTHETASE 1	polymer	486	54584.7	12	UniProt (P0A590) Pfam (PF03951) Pfam (PF00120) UniProt (by SIFTS) (P9WN39) In PDB	MYCOBACTERIUM TUBERCULOSIS	GLUTAMATE--AMMONIA LIGASE 1
2	H, I, J, K, L...	1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione	non-polymer		424.3	12	Chemie (1AZ)
3	H, I, J, K, L...	CHLORIDE ION	non-polymer		35.5	12	Chemie (CL)
4		water	water		18.0	1536	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: -7 - 1 (PDB: 2WGS)
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 478 (UniProt: P0A590)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	655016.8
Non-Polymers*	Number of molecules	24
	Total formula weight	5516.8
All*	Total formula weight	660533.6

*Water molecules are not included.