2WGS
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | GLUTAMINE SYNTHETASE 1 | polymer | 486 | 54584.7 | 12 | UniProt (P0A590) Pfam (PF03951) Pfam (PF00120) UniProt (by SIFTS) (P9WN39) In PDB | MYCOBACTERIUM TUBERCULOSIS | GLUTAMATE--AMMONIA LIGASE 1 |
2 | H, I, J, K, L... | 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione | non-polymer | 424.3 | 12 | Chemie (1AZ) | |||
3 | H, I, J, K, L... | CHLORIDE ION | non-polymer | 35.5 | 12 | Chemie (CL) | |||
4 | water | water | 18.0 | 1536 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: -7 - 1 (PDB: 2WGS)
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 478 (UniProt: P0A590)
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 478 (UniProt: P0A590)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 655016.8 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 5516.8 | |
All* | Total formula weight | 660533.6 |