2WGH
Human Ribonucleotide reductase R1 subunit (RRM1) in complex with dATP and Mg.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT | polymer | 676 | 77164.0 | 2 | UniProt (P23921) Pfam (PF00317) Pfam (PF02867) | HOMO SAPIENS (HUMAN) | RIBONUCLEOTIDE REDUCTASE R1 SUBUNIT, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M1, RIBONUCLEOTIDE REDUCTASE LARGE SUBUNIT |
| 2 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, F (A, B) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A, B: 75 - 742 (UniProt: P23921)
| PDB | External Database | Details |
|---|---|---|
| Met 74 | - | expression tag |
| Ala 743 | - | expression tag |
| His 744 | - | expression tag |
| His 745 | - | expression tag |
| His 746 | - | expression tag |
| His 747 | - | expression tag |
| His 748 | - | expression tag |
| His 749 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 154328.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1123.1 | |
| All* | Total formula weight | 155451.0 |
