2WEV
Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design
Replaces: 2C5PEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN-DEPENDENT KINASE 2, P33 PROTEIN KINASE |
2 | B, D | CYCLIN-A2 | polymer | 260 | 29867.5 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN-A |
3 | E, F | ARG-ARG-B3L-MEA | polymer | 6 | 644.8 | 2 | SYNTHETIC CONSTRUCT | ||
4 | A, C | [4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE | non-polymer | 328.3 | 2 | Chemie (CK7) | |||
5 | water | water | 18.0 | 545 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 128977.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 656.7 | |
All* | Total formula weight | 129634.4 |