2WER

Yeast Hsp90 N-terminal domain LI-IV mutant with Radicicol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ATP-DEPENDENT MOLECULAR CHAPERONE HSP82	polymer	220	24859.4	2	UniProt (P02829) Pfam (PF02518)	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, HSP90,82 KDA HEAT SHOCK PROTEIN
2	C, D (A, B)	RADICICOL	non-polymer		364.8	2	Chemie (RDC) PubChem (5033) PubChem (23304243) PubChem (23351218) PubChem (23375462) PubChem (24871113) PubChem (24883610) PubChem (44323216) PubChem (44634642) PubChem (509980) PubChem (51535441) PubChem (52224359) PubChem (52224360) PubChem (45933581) PubChem (56846487) PubChem (57685060) PubChem (57729285) PubChem (59114079) PubChem (60028429) PubChem (60043244) PubChem (60046279) PubChem (5289273) PubChem (5311380) PubChem (155901071) PubChem (5353918) PubChem (5359013) PubChem (71684643) PubChem (6323491) PubChem (90798921) PubChem (9799192) PubChem (9863893) PubChem (91150137) PubChem (91414470) PubChem (91421888) PubChem (91499444) PubChem (92265824) PubChem (10915493) PubChem (11268547) PubChem (89174685) PubChem (92966529) PubChem (98043730) PubChem (98043729) PubChem (123740891) PubChem (124918602) PubChem (134688667) PubChem (135121972) PubChem (137433107) PubChem (142109646) PubChem (152743492) PubChem (163001975) PubChem (163001976) PubChem (173786049) PubChem (16196977)
3	E, F (A, B)	water	water		18.0	284	Chemie (HOH)

Sequence modifications

A, B: 1 - 220 (UniProt: P02829)

PDB	External Database	Details
Ile 34	Leu 34	engineered mutation
Val 35	Ile 35	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49718.7
Non-Polymers*	Number of molecules	2
	Total formula weight	729.6
All*	Total formula weight	50448.3

*Water molecules are not included.