2WEO
Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBONIC ANHYDRASE 2 | polymer | 259 | 29157.9 | 1 | UniProt (P00918) Pfam (PF00194) | HOMO SAPIENS (HUMAN) | CARBONIC ANHYDRASE II, CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CA-II, CAC |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 3-fluorobenzenesulfonamide | non-polymer | 175.2 | 1 | Chemie (FBW) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | F (A) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29157.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 410.8 | |
| All* | Total formula weight | 29568.7 |
