2WE2

EBV dUTPase double mutant Gly78Asp-Asp131Ser with dUMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE	polymer	286	31695.3	1	UniProt (P03195) Pfam (PF00692)	HUMAN HERPESVIRUS 4 (EPSTEIN-BARR VIRUS)	DUTP PYROPHOSPHATASE, DUTPASE
2	B (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	C (A)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	1	Chemie (UMP)
4	D (A)	water	water		18.0	299	Chemie (HOH)

Sequence modifications

A: -7 - 0 (PDB: 2WE2)
A: 1 - 278 (UniProt: P03195)

PDB	External Database	Details
Asp 78	Gly 78	engineered mutation
Ser 131	Asp 131	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31695.3
Non-Polymers*	Number of molecules	2
	Total formula weight	404.2
All*	Total formula weight	32099.6

*Water molecules are not included.