2WD2
A chimeric microtubule disruptor with efficacy on a taxane resistant cell line
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBONIC ANHYDRASE 2 | polymer | 259 | 29157.9 | 1 | UniProt (P00918) Pfam (PF00194) | HOMO SAPIENS (HUMAN) | CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE C, CA-II, CACCARBONIC ANHYDRASE II |
| 2 | B, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | C (A) | 7-methoxy-2-(3-methoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-yl sulfamate | non-polymer | 378.4 | 1 | Chemie (MS5) | |||
| 4 | E, F, G (A) | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
| 5 | H (A) | water | water | 18.0 | 245 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29157.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 647.3 | |
| All* | Total formula weight | 29805.2 |
