2WD1
Human c-Met Kinase in complex with azaindole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HEPATOCYTE GROWTH FACTOR RECEPTOR | polymer | 292 | 33048.4 | 1 | UniProt (P08581) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | SCATTER FACTOR RECEPTOR, HGF/SF RECEPTOR, MET PROTO-ONCOGENE TYROSINE KINASE, C-MET |
| 2 | B (A) | 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE | non-polymer | 346.3 | 1 | Chemie (ZZY) | |||
| 3 | C, D (A) | GAMMA-BUTYROLACTONE | non-polymer | 86.1 | 2 | Chemie (GBL) | |||
| 4 | E (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 1055 - 1346 (UniProt: P08581)
| PDB | External Database | Details |
|---|---|---|
| Leu 1272 | Val 1272 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33048.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 518.5 | |
| All* | Total formula weight | 33566.9 |
