2WCG
X-ray structure of acid-beta-glucosidase with N-octyl(cyclic guanidine)-nojirimycin in the active site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | GLUCOSYLCERAMIDASE | polymer | 505 | 56589.3 | 2 | UniProt (B2R6A7) Pfam (PF02055) Pfam (PF17189) UniProt (by SIFTS) (P04062) In PDB | HOMO SAPIENS (HUMAN) | |
2 | C, D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
3 | A, B | alpha-L-fucopyranose | non-polymer | 164.2 | 2 | Chemie (FUC) | |||
4 | A, B | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
5 | A, B | N-[(3E,5R,6R,7S,8R,8AR)-5,6,7,8-TETRAHYDROXYHEXAHYDROIMIDAZO[1,5-A]PYRIDIN-3(2H)-YLIDENE]OCTAN-1-AMINIUM | non-polymer | 316.4 | 2 | Chemie (MT5) | |||
6 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
7 | water | water | 18.0 | 741 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 113178.6 | |
Branched | Number of molecules | 2 |
Total formula weight | 1173.1 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2184.8 | |
All* | Total formula weight | 116536.5 |