2WCG

X-ray structure of acid-beta-glucosidase with N-octyl(cyclic guanidine)-nojirimycin in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUCOSYLCERAMIDASE	polymer	505	56589.3	2	UniProt (B2R6A7) Pfam (PF02055) Pfam (PF17189) UniProt (by SIFTS) (P04062)	HOMO SAPIENS (HUMAN)
2	C, D (C, D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
3	E, N (A, B)	alpha-L-fucopyranose	non-polymer		164.2	2	Chemie (FUC)
4	F, G, H, I, J... (A, B)	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
5	L, U (A, B)	N-[(3E,5R,6R,7S,8R,8AR)-5,6,7,8-TETRAHYDROXYHEXAHYDROIMIDAZO[1,5-A]PYRIDIN-3(2H)-YLIDENE]OCTAN-1-AMINIUM	non-polymer		316.4	2	Chemie (MT5)
6	M, V (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
7	W, X (A, B)	water	water		18.0	741	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2WCG)
A, B: 498 - 503 (PDB: 2WCG)
A, B: 1 - 497 (UniProt: B2R6A7)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	113178.6
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	18
	Total formula weight	2184.8
All*	Total formula weight	116536.5

*Water molecules are not included.