2WBK
Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BETA-MANNOSIDASE | polymer | 847 | 98101.9 | 2 | UniProt (Q8AAK6) Pfam (PF22666) Pfam (PF00703) Pfam (PF17786) Pfam (PF17753) | BACTEROIDES THETAIOTAOMICRON | |
| 2 | AA, AB, C, CA, CB... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 38 | Chemie (EDO) | |||
| 3 | E, EA, FA, GB, R... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 4 | G, HA (A, B) | 2,4-dinitrophenyl 2-deoxy-2-fluoro-beta-D-mannopyranoside | non-polymer | 348.2 | 2 | Chemie (M2F) | |||
| 5 | BA, BB, DB, S, T... (A, B) | BROMIDE ION | non-polymer | 79.9 | 12 | Chemie (BR) | |||
| 6 | JB, KB (A, B) | water | water | 18.0 | 1149 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 864 (UniProt: Q8AAK6)
A, B: 865 - 872 (PDB: 2WBK)
| PDB | External Database | Details |
|---|---|---|
| Gln 555 | Glu 555 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 196203.8 | |
| Non-Polymers* | Number of molecules | 59 |
| Total formula weight | 4262.1 | |
| All* | Total formula weight | 200465.9 |
