2WBE
Kinesin-5-Tubulin Complex with AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TUBULIN ALPHA-1D CHAIN | polymer | 451 | 50107.2 | 1 | UniProt (P02550) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (Q2HJ86) | BOS TAURUS (CATTLE) | ALPHA-BETA-TUBULIN, TUBA1D |
| 2 | B (B) | TUBULIN BETA-2B CHAIN | polymer | 445 | 49907.8 | 1 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (Q6B856) | BOS TAURUS (CATTLE) | ALPHA-BETA-TUBULIN, TUBB2B |
| 3 | C (C) | BIPOLAR KINESIN KRP-130 | polymer | 373 | 41911.6 | 1 | UniProt (P46863) Pfam (PF00225) | DROSOPHILA MELANOGASTER (FRUIT FLY) | KLP61F, KINESIN-LIKE PROTEIN KLP61F, KLP2 |
| 4 | D, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | E (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 6 | F (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 7 | G (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) | |||
| 8 | H (C) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) |
Sequence modifications
A: 1 - 451 (UniProt: P02550)
C: -11 - 356 (UniProt: P46863)
| PDB | External Database | Details |
|---|---|---|
| Gly 265 | Ala 265 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -16 | - | expression tag |
| His -15 | - | expression tag |
| Met -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Ser -12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 141926.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2375.1 | |
| All* | Total formula weight | 144301.7 |
