2WAY

Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	ATP-DEPENDENT RNA HELICASE DDX6	polymer	193	22475.7	2	UniProt (P26196) Pfam (PF00271)	HOMO SAPIENS (HUMAN)	HUMAN DDX6, DEAD BOX PROTEIN 6, ATP-DEPENDENT RNA HELICASE P54, ONCOGENE RCK
2	B, D (B, D)	ENHANCER OF MRNA-DECAPPING PROTEIN 3	polymer	44	5069.4	2	UniProt (Q96F86)	HOMO SAPIENS (HUMAN)	HUMAN EDC3, LSM16 HOMOLOG, YJEF DOMAIN-CONTAINING PROTEIN 1, YJEF N-TERMINAL DOMAIN-CONTAINING PROTEIN 2, YJEF_N2, HYJEF_N2
3	E, F, G, H (A, C)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	I, J, K, L (A, B, C, D)	water	water		18.0	111	Chemie (HOH)

Sequence modifications

A, C: 280 - 284 (PDB: 2WAY)
A, C: 285 - 472 (UniProt: P26196)
B, D: 185 - 191 (PDB: 2WAY)
B, D: 192 - 228 (UniProt: Q96F86)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55090.2
Non-Polymers*	Number of molecules	4
	Total formula weight	368.4
All*	Total formula weight	55458.5

*Water molecules are not included.