2W80

Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, G (A, B, E, G)	COMPLEMENT FACTOR H	polymer	123	14222.0	4	UniProt (P08603) Pfam (PF00084)	HOMO SAPIENS (HUMAN)	H FACTOR 1
2	C, D, F, H (C, D, F, H)	FACTOR H BINDING PROTEIN	polymer	253	26983.1	4	UniProt (Q9JXV4) Pfam (PF20937) Pfam (PF08794)	NEISSERIA MENINGITIDIS
3	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	508	Chemie (HOH)

Sequence modifications

A, B, E, G: 321 - 443 (UniProt: P08603)

PDB	External Database	Details
His 402	Tyr 402	variant

C, D, F, H: 71 - 320 (UniProt: Q9JXV4)
C, D, F, H: 321 - 323 (PDB: 2W80)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	164820.4
All*	Total formula weight	164820.4

*Water molecules are not included.