2W7X
Cellular inhibition of checkpoint kinase 2 and potentiation of cytotoxic drugs by novel Chk2 inhibitor PV1019
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SERINE/THREONINE-PROTEIN KINASE CHK2 | polymer | 323 | 36562.2 | 1 | UniProt (O96017) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CHECKPOINT KINASE 2, CDS1 |
| 2 | A | N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide | non-polymer | 379.4 | 1 | Chemie (D1A) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36562.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 589.8 | |
| All* | Total formula weight | 37152.1 |
