2W7O

Structure and Activity of Bypass Synthesis by Human DNA Polymerase Kappa Opposite the 7,8-Dihydro-8-oxodeoxyguanosine Adduct

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA POLYMERASE KAPPA	polymer	508	58038.3	2	UniProt (Q9UBT6) Pfam (PF00817) Pfam (PF11798) Pfam (PF11799)	HOMO SAPIENS (HUMAN)	DINB, DINP
2	C, E (E, P)	5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'	polymer	13	4096.7	2
3	D, F (F, T)	5'-D(TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP*TP* TP*CP*CP*CP*CP*C)-3'	polymer	18	5388.5	2
4	G, J (A, B)	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (DGT)
5	H, I, K, L (A, B)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
6	M, N, O, P (A, B, P, T)	water	water		18.0	30	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	135046.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1174.7
All*	Total formula weight	136221.6

*Water molecules are not included.