2W7A

Structure of the human LINE-1 ORF1p central domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LINE-1 ORF1P	polymer	100	11626.0	2	UniProt (Q15605) Pfam (PF02994) UniProt (by SIFTS) (Q9UN81)	HOMO SAPIENS (HUMAN)	ORF1 CODES FOR A 40 KDA PRODUCT
2	C (B)	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
3	D, E (A, B)	water	water		18.0	298	Chemie (HOH)

Sequence modifications

A, B: 153 - 156 (PDB: 2W7A)
A, B: 157 - 252 (UniProt: Q15605)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23252.0
Non-Polymers*	Number of molecules	1
	Total formula weight	102.0
All*	Total formula weight	23354.0

*Water molecules are not included.