2W5V

Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Mg bound in the M3 site.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ALKALINE PHOSPHATASE	polymer	375	40470.3	2	UniProt (Q9KWY4)	ANTARCTIC BACTERIUM TAB5	TAB5 ALKALINE PHOSPHATASE MUTANT
2	C, D, G, H (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, F, I, J (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	K, L (A, B)	water	water		18.0	589	Chemie (HOH)

Sequence modifications

A, B: 1 - 375 (UniProt: Q9KWY4)

PDB	External Database	Details
Ser 58	Glu 58	conflict
Asp 135	His 135	engineered mutation
Ala 198	Gly 198	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80940.7
Non-Polymers*	Number of molecules	8
	Total formula weight	358.9
All*	Total formula weight	81299.5

*Water molecules are not included.