2W3O
Crystal structure of the human PNKP FHA domain in complex with an XRCC1-derived phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE | polymer | 113 | 12117.6 | 2 | UniProt (Q96T60) Pfam (PF17913) In PDB | HOMO SAPIENS (HUMAN) | FHA DOMAIN OF POLYNUCLEOTIDE KINASE 3' PHOSPHATASE, DNA 5'-KINASE/3'-PHOSPHATASE, POLYNUCLEOTIDE 5'-HYDROXYL-KINASE, POLYNUCLEOTIDE 3'-PHOSPHATASE |
| 2 | C, D | DNA REPAIR PROTEIN XRCC1 | polymer | 8 | 1015.8 | 2 | UniProt (P18887) In PDB | HOMO SAPIENS | X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 1, XRCC1-DERIVED PHOSPHOPEPTIDE |
| 3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A, B: -2 - 0 (PDB: 2W3O)
A, B: 1 - 110 (UniProt: Q96T60)
A, B: 1 - 110 (UniProt: Q96T60)
| PDB | External Database | Details |
|---|---|---|
| Glu 18 | Gly 18 | SEE REMARK 999 |
| Glu 99 | Leu 99 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 26266.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 240.5 | |
| All* | Total formula weight | 26507.2 |
