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2W3M

HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND FOLATE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DIHYDROFOLATE REDUCTASEpolymer18721480.72UniProt (P00374)
Pfam (PF00186)
HOMO SAPIENS (HUMAN)
2C, E
(A, B)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.42Chemie (NDP)
3D, F
(A, B)
FOLIC ACIDnon-polymer441.42Chemie (FOL)
4G, H
(A, B)
waterwater18.0494Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42961.4
Non-Polymers*Number of molecules4
Total formula weight2373.6
All*Total formula weight45335.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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