2W1H
Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE, CDK2 |
| 2 | B (A) | N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE | non-polymer | 303.3 | 1 | Chemie (L0F) | |||
| 3 | C (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33976.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 303.3 | |
| All* | Total formula weight | 34279.8 |
