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2W1H

Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi- targeted Kinase Inhibitor with Potent Aurora Kinase Activity

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACELL DIVISION PROTEIN KINASE 2polymer29833976.51UniProt (P24941)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)P33 PROTEIN KINASE, CDK2
2AN-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDEnon-polymer303.31Chemie (L0F)
3waterwater18.0221Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33976.5
Non-Polymers*Number of molecules1
Total formula weight303.3
All*Total formula weight34279.8
*Water molecules are not included.

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PDB entries from 2024-09-18

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