2W1C

Structure determination of Aurora Kinase in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SERINE/THREONINE-PROTEIN KINASE 6	polymer	275	32317.9	1	UniProt (O14965) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	AURORA KINASE A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE, AURORA A, AURORA-A, AURORA-RELATED KINASE 1, HARK1
2	B (A)	4-{[2-(4-{[(4-FLUOROPHENYL)CARBONYL]AMINO}-1H-PYRAZOL-3-YL)-1H-BENZIMIDAZOL-6-YL]METHYL}MORPHOLIN-4-IUM	non-polymer		421.4	1	Chemie (L0C)

Sequence modifications

A: 121 - 121 (PDB: 2W1C)
A: 390 - 395 (PDB: 2W1C)
A: 122 - 389 (UniProt: O14965)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32317.9
Non-Polymers*	Number of molecules	1
	Total formula weight	421.4
All*	Total formula weight	32739.3

*Water molecules are not included.