2W17

CDK2 in complex with the imidazole pyrimidine amide, compound (S)-8b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CELL DIVISION PROTEIN KINASE 2	polymer	299	34002.5	1	UniProt (P24941) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE
2	B (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
3	C (A)	N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine	non-polymer		451.5	1	Chemie (I19)
4	D (A)	water	water		18.0	150	Chemie (HOH)

Sequence modifications

A: 0 - 0 (PDB: 2W17)
A: 1 - 298 (UniProt: P24941)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34002.5
Non-Polymers*	Number of molecules	2
	Total formula weight	510.6
All*	Total formula weight	34513.1

*Water molecules are not included.