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2VZW

X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
PROBABLE HISTIDINE KINASE RESPONSE REGULATORpolymer14916357.42UniProt (O53473)
Pfam (PF01590)
UniProt (by SIFTS) (P9WGK1)
MYCOBACTERIUM TUBERCULOSISGAF FAMILY PROTEIN, DOST
2C, E
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
3D, G
(A, B)
ACETATE IONnon-polymer59.02Chemie (ACT)
4F
(B)
OXYGEN MOLECULEnon-polymer32.01Chemie (OXY)
5H, I
(A, B)
waterwater18.0109Chemie (HOH)
Sequence modifications
A, B: 61 - 208 (UniProt: O53473)
PDBExternal DatabaseDetails
Gly 60-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32714.9
Non-Polymers*Number of molecules5
Total formula weight1383.1
All*Total formula weight34098.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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