2VWC

STRUCTURE OF THE HSP90 INHIBITOR MACBECIN BOUND TO THE N-TERMINUS OF YEAST HSP90.

Replaces:  2VLS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ATP-DEPENDENT MOLECULAR CHAPERONE HSP82	polymer	219	24776.3	1	UniProt (P02829) Pfam (PF02518)	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM, 82 KDA HEAT SHOCK PROTEIN
2	B (A)	MACBECIN	non-polymer		558.7	1	Chemie (BC2) PubChem (20786720) PubChem (22524979) PubChem (23229054) PubChem (177408296) PubChem (23425243) PubChem (24199491) PubChem (433447) PubChem (59996476) PubChem (67495410) PubChem (67495412) PubChem (70824163) PubChem (5458728) PubChem (5477570) PubChem (5858310) PubChem (10392986) PubChem (10886216) PubChem (98218987) PubChem (98218989) PubChem (99719506) PubChem (98218988) PubChem (98218990) PubChem (6436263) PubChem (122173109) PubChem (138107724) PubChem (13267717) PubChem (162984785) PubChem (137347516) PubChem (162984789) PubChem (137699317) PubChem (140580354) PubChem (156595903) PubChem (162984786) PubChem (162984787) PubChem (162984788) PubChem (168012345) PubChem (168314096) PubChem (171318957) PubChem (171337504) PubChem (172014669)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
4	D (A)	water	water		18.0	119	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	24776.3
Non-Polymers*	Number of molecules	2
	Total formula weight	650.8
All*	Total formula weight	25427.0

*Water molecules are not included.