2VU3
Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H- pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CDK2, P33 PROTEIN KINASE, CYCLIN DEPENDENT KINASE KINASE 2 |
| 2 | A | 4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide | non-polymer | 382.2 | 1 | Chemie (LZE) | |||
| 3 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33976.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 382.2 | |
| All* | Total formula weight | 34358.7 |
