2VTI
Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H- pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CDK2, P33 PROTEIN KINASE |
2 | A | N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide | non-polymer | 316.3 | 1 | Chemie (LZ3) | |||
3 | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33976.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 316.3 | |
All* | Total formula weight | 34292.8 |