2VT0

X-ray structure of a conjugate with conduritol-beta-epoxide of acid-beta-glucosidase overexpressed in cultured plant cells

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUCOSYLCERAMIDASE	polymer	505	56589.3	2	UniProt (Q9BDT0) Pfam (PF02055) Pfam (PF17189) UniProt (by SIFTS) (P04062)	HOMO SAPIENS (HUMAN)	BETA-GLUCOCEREBROSIDASE, ACID BETA-GLUCOSIDASE, D-GLUCOSYL-N-ACYLSPHINGOSINE GLUCOHYDROLASE, GLUCOSIDASE
2	C (C)	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G73622RM)
3	D (D)	alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G11971MR)
4	E, L (A, B)	(1R,2R,3S,4S,5S,6S)-CYCLOHEXANE-1,2,3,4,5,6-HEXOL	non-polymer		180.2	2	Chemie (CBU)
5	F, G, H, I, J... (A, B)	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
6	Q, R (A, B)	water	water		18.0	464	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2VT0)
A, B: 498 - 503 (PDB: 2VT0)
A, B: 1 - 497 (UniProt: Q9BDT0)

PDB	External Database	Details
Pro 55	Thr 94	conflict
His 495	Arg 534	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	113178.6
Branched	Number of molecules	2
	Total formula weight	1303.2
Non-Polymers*	Number of molecules	12
	Total formula weight	1320.9
All*	Total formula weight	115802.7

*Water molecules are not included.