2VS5
THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE | polymer | 286 | 33761.8 | 2 | UniProt (P14769) Pfam (PF03414) | BOS TAURUS (BOVINE) | GALACTOSYLTRANSFERASE, UDP-GALACTOSE\: BETA-D-GALACTOSYL-1,4-N-ACETYL-D-GLUCOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ALPHA-1,3 GALACTOSYLTRANSFERASE |
| 2 | C, D, F (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 3 | E, G (A, B) | GALACTOSE-URIDINE-5'-DIPHOSPHATE | non-polymer | 566.3 | 2 | Chemie (GDU) | |||
| 4 | H (B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 723 | Chemie (HOH) |
Sequence modifications
A, B: 80 - 365 (UniProt: P14769)
| PDB | External Database | Details |
|---|---|---|
| Gln 317 | Glu 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67523.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1415.6 | |
| All* | Total formula weight | 68939.3 |
