2VS3
THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE | polymer | 289 | 34089.2 | 2 | UniProt (P14769) Pfam (PF03414) | BOS TAURUS (BOVINE) | GALACTOSYLTRANSFERASE, UDP-GALACTOSE\: BETA-D-GALACTOSYL-1,4-N-ACETYL-D-GLUCOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ALPHA-1,3 GALACTOSYLTRANSFERASE |
| 2 | C, D (C, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | branched | 383.3 | 2 | In PDB BIRD (PRD_900019) GlyTouCan (G79333MY) | N-acetyl-alpha-lactosamine | ||
| 3 | E, G (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | F, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
A, B: 80 - 368 (UniProt: P14769)
| PDB | External Database | Details |
|---|---|---|
| Asn 316 | Asp 316 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68178.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 766.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 918.2 | |
| All* | Total formula weight | 69863.3 |
