2VRX

Structure of Aurora B kinase in complex with ZM447439

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SERINE/THREONINE-PROTEIN KINASE 12-A	polymer	285	33652.0	2	UniProt (Q6DE08) Pfam (PF00069)	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	AURORA-B-A, AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, PROTEIN KINASE
2	C, D (C, D)	INNER CENTROMERE PROTEIN A	polymer	43	4976.6	2	UniProt (O13024) Pfam (PF03941)	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	MITOTIC PHOSPHOPROTEIN 130, XL-INCENP
3	E, F (A, B)	N-(4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino}phenyl)benzamide	non-polymer		513.6	2	Chemie (447)
4	G, H, I, J (A, B, C, D)	water	water		18.0	594	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77257.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1027.2
All*	Total formula weight	78284.4

*Water molecules are not included.