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2VRW

Critical structural role for the PH and C1 domains of the Vav1 exchange factor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1polymer18420462.71UniProt (P63000)
Pfam (PF00071)
HOMO SAPIENS (HUMAN)P21-RAC1, RAS- LIKE PROTEIN TC25, CELL MIGRATION-INDUCING GENE 5 PROTEIN, RAC1
2B
(B)
PROTO-ONCOGENE VAVpolymer40647499.21UniProt (P27870)
Pfam (PF00621)
Pfam (PF00169)
Pfam (PF00130)
MUS MUSCULUS (MOUSE)P95VAV, VAV1
3C, D
(B)
ZINC IONnon-polymer65.42Chemie (ZN)
4E, F
(A, B)
waterwater18.0471Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67962.0
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight68092.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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