2VR4
Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BETA-MANNOSIDASE | polymer | 846 | 97989.7 | 2 | UniProt (Q8AAK6) Pfam (PF22666) Pfam (PF00703) Pfam (PF17786) Pfam (PF17753) In PDB | BACTEROIDES THETAIOTAOMICRON | |
2 | A, B | (2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol | non-polymer | 247.3 | 2 | Chemie (17B) | |||
3 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 50 | Chemie (EDO) | |||
4 | A, B | BROMIDE ION | non-polymer | 79.9 | 8 | Chemie (BR) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) | |||
6 | water | water | 18.0 | 1149 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 195979.5 | |
Non-Polymers* | Number of molecules | 71 |
Total formula weight | 4627.2 | |
All* | Total formula weight | 200606.7 |