2VQU
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | BETA-MANNOSIDASE | polymer | 846 | 97874.6 | 2 | UniProt (Q8AAK6) Pfam (PF00703) Pfam (PF17786) Pfam (PF17753) In PDB | BACTEROIDES THETAIOTAOMICRON | |
| 2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 55 | Chemie (EDO) | |||
| 3 | A, B | (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL | non-polymer | 163.2 | 2 | Chemie (NOY) | |||
| 4 | A, B | BROMIDE ION | non-polymer | 79.9 | 12 | Chemie (BR) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 1230 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 864 (UniProt: Q8AAK6)
A, B: 865 - 871 (PDB: 2VQU)
| PDB | External Database | Details |
|---|---|---|
| Ala 645 | Trp 645 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 195749.2 | |
| Non-Polymers* | Number of molecules | 77 |
| Total formula weight | 4982.6 | |
| All* | Total formula weight | 200731.7 |
