2VQ5

X-ray structure of Norcoclaurine synthase from Thalictrum flavum in complex with dopamine and hydroxybenzaldehyde

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	S-NORCOCLAURINE SYNTHASE	polymer	201	22606.2	2	UniProt (Q67A25) Pfam (PF00407)	THALICTRUM FLAVUM	NORCOCLAURINE SYNTHASE FROM THALICTRUM FLAVUM
2	C, D (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
3	E, F, G, I, J (A, B)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
4	H, L (A, B)	P-HYDROXYBENZALDEHYDE	non-polymer		122.1	2	Chemie (HBA)
5	K (B)	L-DOPAMINE	non-polymer		153.2	1	Chemie (LDP)
6	M, N (A, B)	water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, B: 16 - 210 (UniProt: Q67A25)

PDB	External Database	Details
Mse 16	Thr 16	engineered mutation
Thr 17	Ile 17	engineered mutation
Gly 18	Asn 18	engineered mutation
Ser 19	Cys 19	engineered mutation

A, B: 211 - 216 (PDB: 2VQ5)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45212.4
Non-Polymers*	Number of molecules	10
	Total formula weight	692.8
All*	Total formula weight	45905.2

*Water molecules are not included.