2VOM

Structural basis of human triosephosphate isomerase deficiency. Mutation E104D and correlation to solvent perturbation.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TRIOSEPHOSPHATE ISOMERASE	polymer	250	26700.4	4	UniProt (P60174) Pfam (PF00121)	HOMO SAPIENS (HUMAN)	TIM
2	E, F, G, H (A, B, C, D)	water	water		18.0	611	Chemie (HOH)

Sequence modifications

A, B, C, D: -1 - 0 (PDB: 2VOM)
A, B, C, D: 1 - 248 (UniProt: P60174)

PDB	External Database	Details
Asp 104	Glu 105	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	106801.5
All*	Total formula weight	106801.5

*Water molecules are not included.