2VO7
Structure of PKA complexed with 4-(4-Chlorobenzyl)-1-(7H-pyrrolo(2,3- d)pyrimidin-4-yl)piperidin-4-ylamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT | polymer | 351 | 40837.6 | 1 | UniProt (P00517) Pfam (PF00069) | BOS TAURUS (BOVINE) | PROTEIN KINASE A, PKA C-ALPHA |
| 2 | B (I) | CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA | polymer | 20 | 2226.4 | 1 | UniProt (P61925) | HOMO SAPIENS | PKI, PKI-ALPHA, CAMP- DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN ISOFORM |
| 3 | C, D (A) | 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium | non-polymer | 342.8 | 2 | Chemie (M05) | |||
| 4 | E, F (A, I) | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43064.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 685.7 | |
| All* | Total formula weight | 43749.7 |
