2VK1
Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant D28A in complex with its substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | PYRUVATE DECARBOXYLASE ISOZYME 1 | polymer | 563 | 61513.0 | 4 | UniProt (P06169) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) | SACCHAROMYCES CEREVISIAE (YEAST) | PYRUVATE DECARBOXYLASE |
| 2 | E, I, M, Q (A, B, C, D) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 4 | Chemie (TPP) | |||
| 3 | F, J, N, R (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, H, K, L, O... (A, B, C, D) | PYRUVIC ACID | non-polymer | 88.1 | 8 | Chemie (PYR) | |||
| 5 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 1558 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 563 (UniProt: P06169)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | Asp 28 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 246052.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2503.0 | |
| All* | Total formula weight | 248555.0 |
