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2VJV

Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
TRANSPOSASE ORFApolymer15918392.42UniProt (Q933Z0)
Pfam (PF01797)
HELICOBACTER PYLORIIS608 TRANSPOSASE
2C, D
(C, D)
5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3'polymer268003.22HELICOBACTER PYLORILEFT END 26-MER HAIRPIN
3E, F
(E, F)
5'-D(*DT*DA*DT*DT*DA*DCP)-3'polymer61783.22HELICOBACTER PYLORI6-MER LEFT END CLEAVAGE SITE
4G, H, I
(C, D, E)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5J, K, L, M, N...
(A, B, C, D, E...)
waterwater18.0275Chemie (HOH)
Sequence modifications
A, B: -3 - 1 (PDB: 2VJV)
A, B: 2 - 155 (UniProt: Q933Z0)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight56357.6
Non-Polymers*Number of molecules3
Total formula weight72.9
All*Total formula weight56430.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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