2VJE
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 UBIQUITIN-PROTEIN LIGASE MDM2 | polymer | 64 | 7094.7 | 2 | UniProt (Q00987) Pfam (PF13920) | HOMO SAPIENS (HUMAN) | P53-BINDING PROTEIN MDM2, ONCOPROTEIN MDM2, DOUBLE MINUTE 2 PROTEIN, HDM2, MDM2 |
| 2 | B, D (B, D) | MDM4 PROTEIN | polymer | 63 | 7076.5 | 2 | UniProt (O15151) Pfam (PF13920) | HOMO SAPIENS (HUMAN) | P53-BINDING PROTEIN MDM4, MDM2-LIKE P53-BINDING PROTEIN, MDMX PROTEIN, DOUBLE MINUTE 4 PROTEIN |
| 3 | E, F, G, H, I... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | M (D) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 5 | N (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 28342.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 808.4 | |
| All* | Total formula weight | 29150.8 |
