2VIT
INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | IMMUNOGLOBULIN (IGG1, LAMBDA) | polymer | 210 | 22596.0 | 1 | GenBank (387376) | Mus musculus (house mouse) | |
2 | B | IMMUNOGLOBULIN (IGG1, LAMBDA) | polymer | 221 | 23777.8 | 1 | GenBank (4096752) Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q99LC4) In PDB | Mus musculus (house mouse) | |
3 | C | HEMAGGLUTININ | polymer | 282 | 31178.9 | 1 | UniProt (P03437) Pfam (PF00509) In PDB | Influenza A virus (A/X-31(H3N2)) | |
4 | A, C | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
B: 1 - 221 (GenBank: 4096752)
C: 28 - 309 (UniProt: P03437)
PDB | External Database | Details |
---|---|---|
Gln 3 | Lys 3 | conflict |
Lys 5 | Gln 5 | conflict |
Leu 28 | Ser 28 | conflict |
Ile 30 | Thr 30 | conflict |
Asn 32 | Tyr 32 | conflict |
Leu 63 | His 63 | conflict |
Ile 69 | Phe 69 | conflict |
Lys 83 | Asn 83 | conflict |
Met 92 | Leu 92 | conflict |
Asp 98 | - | insertion |
Phe 99 | - | insertion |
Tyr 100 | - | insertion |
Tyr 102 | His 99 | conflict |
Asp 103 | Gly 100 | conflict |
Phe 105 | - | insertion |
Tyr 106 | - | insertion |
Tyr 107 | - | insertion |
Ala 108 | - | insertion |
Met 109 | - | insertion |
Asp 110 | - | insertion |
Ser 117 | Leu 108 | conflict |
Ser 122 | Ala 113 | conflict |
Pro 135 | Ser 126 | conflict |
PDB | External Database | Details |
---|---|---|
Asp 81 | Asn 97 | modified residue |
Ile 155 | Thr 171 | engineered mutation |
Asp 165 | Asn 181 | modified residue |
Asp 285 | Asn 301 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 77552.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 196.2 | |
All* | Total formula weight | 77749.0 |