2VHW

Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the open and closed conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	ALANINE DEHYDROGENASE	polymer	377	39582.0	6	UniProt (P30234) Pfam (PF05222) Pfam (PF01262) UniProt (by SIFTS) (P9WQB1)	MYCOBACTERIUM TUBERCULOSIS	40 KDA ANTIGEN, TB43
2	G, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
3	H, J, K, L, M... (A, B, C, D, E...)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	6	Chemie (NAI) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (928) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (94865921) PubChem (94865923) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (11250888) PubChem (12309341) PubChem (146167236) PubChem (162951602) PubChem (174084875)
4	O, P, Q, R, S... (A, B, C, D, E...)	water	water		18.0	1512	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 371 (UniProt: P30234)
A, B, C, D, E, F: 372 - 377 (PDB: 2VHW)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	237491.8
Non-Polymers*	Number of molecules	8
	Total formula weight	4041.3
All*	Total formula weight	241533.0

*Water molecules are not included.